Translational Medicine, Organoids & Therapeutic Innovation
INEM supports the development of patient-derived models, organoid technologies, and targeted therapies, bridging experimental research and precision medicine to meet clinical needs.
INEM supports the development of patient-derived models, organoid technologies, and targeted therapies, bridging experimental research and precision medicine to meet clinical needs.
This area explores how cells and tissues adapt, remodel, and repair in response to stress, damage, or disease. Research covers stem cell dynamics, immune and hormonal plasticity, and the molecular pathways driving regeneration, with implications for cancer, chronic inflammation, and regenerative medicine.
Nicolas Dupont has been awarded funding from Université Paris Cité as part of the Crossing Cutting Edges call for proposals, for the project PolluRein (The role of atmospheric particulate matter in chronic kidney disease progression), in collaboration with Prof. Patrice Coll’s laboratory (Laboratoire Interuniversitaire des Systèmes Atmosphériques LISA – UMR 7583).
We are proud to announce that Nina Gruetzmacher, postdoctoral researcher in the Cell Growth by Nutrients Lab - Mario Pende, has been awarded a Marie Skłodowska-Curie Postdoctoral Fellowship (MSCA 2024) under the Horizon Europe programme.
We are thrilled to announce the winners of the 2nd INEM Scientific Photo Contest, which once again highlighted the creativity and scientific diversity of our institute. From cellular landscapes to experimental snapshots, this year’s submissions showcased the fascinating beauty of science.
Jury’s Choice Awards
1st Prize – Mathieu Deygas — Neutro In Vitraux
2nd Prize – Tahina Randresy — First-ever Stem Cells Capable of Growing Forests
3rd Prize – Ana Raquel Cruz — Brief Encounters
Public Vote Winners
We are proud to share that Khaled Tighanimine, former PhD student at INEM under the supervision of Mario Pende and Stefano Fumagalli, has been awarded a Fondation ARC Oberling-Haguenau Thesis Prize during the 2025 Trophées de la Recherche ceremony.
This award highlights Khaled's remarkable doctoral work in the field of cancer research, carried out at INEM.
Our congratulations to Khaled and to all the laureates of this edition!
We are proud to announce that Juliane Da Graça, former PhD student at INEM, has been awarded the 2025 Thesis Prize of the Club Exocytose-Endocytose (Club Exo-Endo).
Juliane carried out her doctoral research in the MEMBRAMICS Lab, under the supervision of Etienne Morel. Her work focused on the role of contact sites between the endoplasmic reticulum and endosomes in the regulation of autophagy, both in physiological and cancer contexts.
New study, in Immunity, led by researchers from the Peter van Endert group uncovers an unexpected immune function for a rare macrophage population in the spleen.
The PI3K (phosphoinositide 3-kinase) signaling pathway is a key driver of metabolic plasticity in aggressive tumors, enabling them to adapt to their microenvironment and resist treatment. However, effectively targeting these cancers remains a major challenge.
In their study published in Nature Communications, Guillaume P. Andrieu et al. propose a promising new therapeutic approach to target leukemias harboring PI3K pathway alterations, which are often associated with poor prognosis and aggressive disease.
Congratulations to Meryem Baghdadi for being featured in Le Point’s 2025 Inventors' Ranking, which highlights 100 scientists whose research is making a difference. This recognition reflects her contributions and dedication to advancing fundamental science.
Kudos to all the laureates!