We are pleased to share that Nicolas Venteclef’s team, Immunity and Metabolism of Diabetes (IMMEDIAB), has been awarded the prestigious FRM team label, a mark of scientific excellence from the Fondation pour la Recherche Médicale, in recognition of the project’s high scientific value and potential impact on metabolic disease research.
We are pleased to share that Fabiola Terzi’s team, Mechanisms and Therapeutic Strategies of Chronic Kidney Disease, has been awarded the prestigious FRM team label, a mark of scientific excellence from the Fondation pour la Recherche Médicale.
This recognition will support their research on chronic kidney disease (CKD), a condition that affects approximately 10% of the global adult population and may lead to end-stage renal failure requiring dialysis or transplantation.
What if a single comic strip could walk you through the life cycle of a phage, and even that of filamentous phages? That’s the clever and creative work of Lison Reboul, a PhD student in the Host-Pathogen Integrative Biology team.
A new study led by the teams of Fabiola Terzi and Marco Pontoglio, recently published in Science Translational Medicine, sheds light on the mechanisms underlying crescentic glomerulonephritis (cGN), a rare and severe kidney disease.
A new publication by the Pende team, in collaboration with the Spassky lab (IBENS), uncovers how the metabolic regulator mTORC1 orchestrates the differentiation of ependymal cells, multiciliated glial cells that line the brain’s ventricles.
The study, published in EMBO Reports, shows that mTORC1 activity promotes progression through an alternative cell cycle required for centriole amplification and multiciliogenesis. Inhibiting mTORC1 preserves the progenitor pool in a quiescent state and impairs key steps in differentiation.
At the recent EMBO Symposium – Infection: pathogens, hosts and microbiomes (May 26–28, 2025, EMBL Heidelberg, Germany), two members of the Schnupf lab were recognised for their work on Segmented Filamentous Bacteria (SFB), a gut commensal with important roles in health and disease.
Ana Raquel Cruz, postdoctoral researcher, was awarded a travel grant and selected to give a talk presenting her thesis work entitled:
Research in this area explores how metabolic cues regulate immune responses, cellular growth, and tissue function, with particular attention to nutrient sensing, hormonal signaling, and metabolic disorders.
This domain focuses on the regulation of immune responses, host-microbe interactions, and the molecular basis of inflammation and infection, including studies on autoimmunity, lymphocyte dynamics, and danger signaling.
Researchers investigate how intracellular organization, membrane remodeling, and signal transduction govern processes like cellular stress, communication, and adaptation, with implications for respiratory, metabolic, and neurological diseases
Teams study how epigenetic modifications and transcriptional programs shape development, immune function, and disease susceptibility, particularly in response to environmental and microbial signals.