Auteurs
Maschalidi S, Nunes-Hasler P, Nascimento CR, Sallent I, Lannoy V, Garfa-Traore M, Cagnard N, Sepulveda FE, Vargas P, Lennon-Duménil AM, van Endert P, Capiod T, Demaurex N, Darrasse-Jèze G, Manoury B
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells
Date revue
Doi
10.1038/s41467-017-01601-5
Revue
Nat Commun
Auteurs
Maatouk L, Compagnion AC, Sauvage MC, Bemelmans AP, Leclere-Turbant S, Cirotteau V, Tohme M, Beke A, Trichet M, Bazin V, Trawick BN, Ransohoff RM, Tronche F, Manoury B, Vyas S
TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons
Doi
10.1038/s41467-018-05680-w
Revue
Nat Commun
Auteurs
Tohme M, Maisonneuve L, Achour K, Dussiot M, Maschalidi S, Manoury B
TLR7 trafficking and signaling in B cells is regulated by the MHCII-associated invariant chain
Date revue
Doi
10.1242/jcs.236711
Revue
J Cell Sci
Auteurs
Cieslak A, Charbonnier G, Tesio M, Mathieu EL, Belhocine M, Touzart A, Smith C, Hypolite G, Andrieu GP, Martens JHA, Janssen-Megens E, Gut M, Gut I, Boissel N, Petit A, Puthier D, Macintyre E, Stunnenberg HG, Spicuglia S, Asnafi V
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation
Date revue
Doi
10.1084/jem.20192360
Revue
J Exp Med
Auteurs
Touzart A, Mayakonda A, Smith C, Hey J, Toth R, Cieslak A, Andrieu GP, Tran Quang C, Latiri M, Ghysdael J, Spicuglia S, Dombret H, Ifrah N, Macintyre E, Lutsik P, Boissel N, Plass C, Asnafi V
Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup
Date revue
Doi
10.1126/scitranslmed.abc4834
Revue
Sci Transl Med
Auteurs
Andrieu GP, Kohn M, Simonin M, Smith CL, Cieslak A, Dourthe MÉ, Charbonnier G, Graux C, Huguet F, Lhéritier V, Dombret H, Spicuglia S, Rousselot P, Boissel N, Asnafi V
PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL
Date revue
Doi
10.1182/blood.2020010081
Revue
Blood
Auteurs
Smith C, Touzart A, Simonin M, Tran-Quang C, Hypolite G, Latiri M, Andrieu GP, Balducci E, Dourthe MÉ, Goyal A, Huguet F, Petit A, Ifrah N, Baruchel A, Dombret H, Macintyre E, Plass C, Ghysdael J, Boissel N, Asnafi V
Harnessing the MYB-dependent TAL1 5'super-enhancer for targeted therapy in T-ALL
Doi
10.1186/s12943-022-01701-x
Revue
Mol Cancer
Auteurs
Pinton A, Courtois L, Doublet C, Cabannes-Hamy A, Andrieu G, Smith C, Balducci E, Cieslak A, Touzart A, Simonin M, Lhéritier V, Huguet F, Balsat M, Dombret H, Rousselot P, Spicuglia S, Macintyre E, Boissel N, Asnafi V
PHF6-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax
Doi
10.1158/1078-0432.CCR-23-2159
Revue
Clin Cancer Res
Auteurs
Balducci E, Steimlé T, Smith C, Villarese P, Feroul M, Payet-Bornet D, Kaltenbach S, Couronné L, Lhermitte L, Touzart A, Dourthe ME, Simonin M, Baruchel A, Dombret H, Ifrah N, Boissel N, Nadel B, Macintyre E, Cieslak A, Asnafi V
TREC mediated oncogenesis in human immature T lymphoid malignancies preferentially involves ZFP36L2
Date revue
Doi
10.1186/s12943-023-01794-y
Revue
Mol Cancer
Auteurs
Canaud G, Bienaimé F, Tabarin F, Bataillon G, Seilhean D, Noël LH, Dragon-Durey MA, Snanoudj R, Friedlander G, Halbwachs-Mecarelli L, Legendre C, Terzi F
Inhibition of the mTORC pathway in the antiphospholipid syndrome
Date revue
Doi
10.1056/NEJMoa1312890
Revue
N Engl J Med