The MENTOR Doctoral Network, coordinated by Mario Pende (INEM, Université Paris Cité), is now accepting applications for 18 PhD positions.

Funded by the MSCA-DN program, MENTOR is a multidisciplinary training network focused on mTOR signaling, a key pathway controlling cell growth and metabolism. Dysregulation of mTOR is implicated in cancer, metabolic disorders, and rare genetic diseases known as mTORopathies.

We are proud to announce that Daryna Batechko, a second-year PhD student in the Panasyuk Lab, has been awarded the prestigious Filfoie - Filière de Santé des Maladies Rares du Foie Prize for her MSc research on Biliary Atresia, a rare pediatric hepato-biliary disease and the leading cause of liver transplantation.

We are delighted to announce that Guillaume Canaud has been awarded the prestigious Prix Innovation 2024 by INSERM. This award recognizes his groundbreaking work in developing the first effective treatment for the rare and severe CLOVES syndrome, offering new hope to affected patients.

Pr. Canaud's innovative approach involves the use of alpelisib, a molecule initially developed for oncology, to inhibit the overactive PIK3CA protein responsible for the syndrome's manifestations. This therapeutic strategy has led to significant improvements in patients' health and quality of life.

We are proud to announce that Matthieu Mahévas, leader of the Autoimmune and B cells immune responses team at INEM, has been awarded a prestigious ERC Consolidator Grant for his project, DIPP-IMMUNE: Dissecting Protective and Pathogenic Long-lasting Humoral Immunity.

The DIPP-IMMUNE project aims to uncover critical mechanisms behind long-term humoral immunity, focusing on three key questions:

Congratulations to Khaled Tighanimine, for receiving the prestigious Prix de la Chancellerie des Universités de Paris - Prix Solennel de Thèse en Sciences!  Khaled's remarkable doctoral work, supervised by Mario Pende and Stefano Fumagalli, explores metabolic adaptations in senescent cells, with a focus on glycerol-3-phosphate and phosphoethanolamine as key actors in lipid remodeling during senescence induction.

This recognition highlights the impactful research happening at INEM. Well done, Khaled, on this well-deserved achievement! 
 

Our Institute proudly celebrates Ganna Panasyuk for receiving the prestigious Sir George K. Radda Outstanding Young Investigator Award at the 2024 Singapore Symposium on Brain-Body Interactions & Neuroscience (November 4–6, 2024, A*STAR Institute, Singapore).

This award honors Dr. Panasyuk’s research on metabolism and signaling in the physiology of diverse organs—a testament to the exceptional work of the Panasyuk Lab.

Congratulations, Ganna, on this remarkable achievement!

We are proud to announce that Mario Pende, head of the Cell growth control by nutrients lab, has received the prestigious Gaston Rousseau Prize for his research on nutrient metabolism and its effects on cell growth, proliferation, and senescence. His work has shed light on metabolic changes that explain why senescent cells accumulate fat in lipid droplets rather than using it for cell membrane construction during growth.