Seminar topic: The puzzle of adult brain stem cell coordination: A functional and evolutionary perspective

Zayna Chaker did her PhD at Université Paris Cité with Dr. Martin Holwenberger in 2015, where she studied the role of growth hormone and insulin like growth factor (IGF) in the regulation of brain regeneration during aging. Then, she moved to Basel Switzerland for a postdoc in Prof. Fiona Doetsch’s lab, where she focused her work on the molecular mechanisms regulating adult brain stem cell behavior and most importantly on the physiological relevance of adult neurogenesis during specific physiological states, such as pregnancy and motherhood. In 2024, Zayna was awarded an FRM funding, and ATIP-Avenir and an ERC starting grant to start her indpendent group in Lyon at the insitute of Functional Genomics (IGFL). 

Her lab is now focused on understanding how brain stem cells coordinate their dynamics at the molecular level across all neurogenic regions of the brain to ensure adaptive behavior, developping computational tools for spatial transcriptomic data analysis and novel non-conventional fish models to compare with the mammalian mouse brain.
 

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