Last 30 publications
2020
Meningococcal disease: A paradigm of type-IV pilus dependent pathogenesis.
Dos Santos Souza I, Maïssa N, Ziveri J, Morand PC, Coureuil M, Nassif X, Bourdoulous S.
Cell Microbiol. 2020 Apr;22(4):e13185. doi: 10.1111/cmi.13185.PMID: 32185901Review.
Clinical and virological responses to a broad-spectrum human monoclonal antibody in an influenza virus challenge study.
Sloan SE, Szretter KJ, Sundaresh B, Narayan KM, Smith P, Skurnik D, Bedard S, Trevejo JM, Oldach D, Shriver Z.
Antiviral Res. 2020 Mar 6:104763. doi: 10.1016/j.antiviral.2020.104763. Online ahead of print.PMID: 32151645
Receptor recognition by meningococcal type IV pili relies on a specific complex N-glycan.
Le Guennec L, Virion Z, Bouzinba-Ségard H, Robbe-Masselot C, Léonard R, Nassif X, Bourdoulous S, Coureuil M.
Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2606-2612. doi: 10.1073/pnas.1919567117. Epub 2020 Jan 21.PMID: 31964828
2019
Airway Mucus Restricts Neisseria meningitidis Away from Nasopharyngeal Epithelial Cells and Protects the Mucosa from Inflammation.
Audry M, Robbe-Masselot C, Barnier JP, Gachet B, Saubaméa B, Schmitt A, Schönherr-Hellec S, Léonard R, Nassif X, Coureuil M.
mSphere. 2019 Dec 4;4(6):e00494-19. doi: 10.1128/mSphere.00494-19.PMID: 31801841Free PMC article.
Author Correction: Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis.
Simonin J, Bille E, Crambert G, Noel S, Dreano E, Edwards A, Hatton A, Pranke I, Villeret B, Cottart CH, Vrel JP, Urbach V, Baatallah N, Hinzpeter A, Golec A, Touqui L, Nassif X, Galietta LJV, Planelles G, Sallenave JM, Edelman A, Sermet-Gaudelus I.
Sci Rep. 2019 Nov 21;9(1):17535. doi: 10.1038/s41598-019-54253-4.PMID: 31754179-Free PMC article.
Multitasking Actors of Staphylococcus aureus Metabolism and Virulence.
Tan X, Coureuil M, Charbit A, Jamet A.
Trends Microbiol. 2020 Jan;28(1):6-9. doi: 10.1016/j.tim.2019.10.013. Epub 2019 Nov 18.PMID: 31753539
Pivotal Role of Mitochondria in Macrophage Response to Bacterial Pathogens.
Ramond E, Jamet A, Coureuil M, Charbit A.
Front Immunol. 2019 Oct 23;10:2461. doi: 10.3389/fimmu.2019.02461. eCollection 2019.PMID: 31708919Free PMC article.Review.
Strategies used by bacterial pathogens to cross the blood-brain barrier.
Le Guennec L, Coureuil M, Nassif X, Bourdoulous S.
Cell Microbiol. 2020 Jan;22(1):e13132. doi: 10.1111/cmi.13132. Epub 2019 Nov 10.PMID: 31658405Review.
Sialic acid mediated mechanical activation of β2 adrenergic receptors by bacterial pili.
Virion Z, Doly S, Saha K, Lambert M, Guillonneau F, Bied C, Duke RM, Rudd PM, Robbe-Masselot C, Nassif X, Coureuil M, Marullo S.
Nat Commun. 2019 Oct 18;10(1):4752. doi: 10.1038/s41467-019-12685-6.PMID: 31628314Free PMC article.
Critical Role of a Sheath Phosphorylation Site On the Assembly and Function of an Atypical Type VI Secretion System.
Ziveri J, Chhuon C, Jamet A, Rytter H, Prigent G, Tros F, Barel M, Coureuil M, Lays C, Henry T, Keep NH, Guerrera IC, Charbit A.
Mol Cell Proteomics. 2019 Dec;18(12):2418-2432. doi: 10.1074/mcp.RA119.001532. Epub 2019 Oct 2.PMID: 31578219
Transketolase of Staphylococcus aureus in the Control of Master Regulators of Stress Response During Infection.
Tan X, Ramond E, Jamet A, Barnier JP, Decaux-Tramoni B, Dupuis M, Euphrasie D, Tros F, Nemazanyy I, Ziveri J, Nassif X, Charbit A, Coureuil M.
J Infect Dis. 2019 Nov 6;220(12):1967-1976. doi: 10.1093/infdis/jiz404.PMID: 31420648
Molecular interactions between Neisseria meningitidis and its human host.
Coureuil M, Jamet A, Bille E, Lécuyer H, Bourdoulous S, Nassif X.
Cell Microbiol. 2019 Nov;21(11):e13063. doi: 10.1111/cmi.13063. Epub 2019 Jun 13.PMID: 31167044Free PMC article.
Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis.
Simonin J, Bille E, Crambert G, Noel S, Dreano E, Edwards A, Hatton A, Pranke I, Villeret B, Cottart CH, Vrel JP, Urbach V, Baatallah N, Hinzpeter A, Golec A, Touqui L, Nassif X, Galietta LJV, Planelles G, Sallenave JM, Edelman A, Sermet-Gaudelus I.
Sci Rep. 2019 Apr 24;9(1):6516. doi: 10.1038/s41598-019-42751-4.PMID: 31019198Free PMC article.
Fulminant arterial vasculitis as an unusual complication of disseminated staphylococcal disease due to the emerging CC1 methicillin-susceptible Staphylococcus aureus clone: a case report.
Vidal C, Moulin F, Nassif X, Galmiche L, Borgel D, Charbit A, Picard C, Mira JP, Lortholary O, Jamet A, Toubiana J.
BMC Infect Dis. 2019 Apr 3;19(1):302. doi: 10.1186/s12879-019-3933-3.PMID: 30943907Free PMC article.
Methods to Study the Roles of β-Arrestins in Meningococcal Signaling.
Virion Z, Marullo S, Coureuil M.
Methods Mol Biol. 2019;1957:325-334. doi: 10.1007/978-1-4939-9158-7_20.PMID: 30919363
Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease.
Denis K, Le Bris M, Le Guennec L, Barnier JP, Faure C, Gouge A, Bouzinba-Ségard H, Jamet A, Euphrasie D, Durel B, Barois N, Pelissier P, Morand PC, Coureuil M, Lafont F, Join-Lambert O, Nassif X, Bourdoulous S.
Nat Microbiol. 2019 Jun;4(6):972-984. doi: 10.1038/s41564-019-0395-8. Epub 2019 Mar 25.PMID: 30911127
Genetic effects on the commensal microbiota in inflammatory bowel disease patients.
Aschard H, Laville V, Tchetgen ET, Knights D, Imhann F, Seksik P, Zaitlen N, Silverberg MS, Cosnes J, Weersma RK, Xavier R, Beaugerie L, Skurnik D, Sokol H.
PLoS Genet. 2019 Mar 8;15(3):e1008018. doi: 10.1371/journal.pgen.1008018. eCollection 2019 Mar.PMID: 30849075Free PMC article.
Chronic Staphylococcus aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence.
Tan X, Coureuil M, Ramond E, Euphrasie D, Dupuis M, Tros F, Meyer J, Nemazanyy I, Chhuon C, Guerrera IC, Ferroni A, Sermet-Gaudelus I, Nassif X, Charbit A, Jamet A.
Clin Infect Dis. 2019 Nov 13;69(11):1937-1945. doi: 10.1093/cid/ciz106.PMID: 30753350
[Meningococcus purpura fulminans, a partially solved mystery].
Lécuyer H, Nassif X, Coureuil M.
Med Sci (Paris). 2018 Dec;34(12):1038-1041. doi: 10.1051/medsci/2018288. Epub 2019 Jan 9.PMID: 30623761French.No abstract available.
2018
A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses.
Le Gallou S, Zhou Z, Thai LH, Fritzen R, de Los Aires AV, Mégret J, Yu P, Kitamura D, Bille E, Tros F, Nassif X, Charbit A, Weller S, Weill JC, Reynaud CA.
J Exp Med. 2018 Aug 6;215(8):2035-2053. doi: 10.1084/jem.20180977. Epub 2018 Jun 29.PMID: 29959173Free PMC article.
An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans.
Lécuyer H, Virion Z, Barnier JP, Matczak S, Bourdoulous S, Bianchini E, Saller F, Borgel D, Nassif X, Coureuil M.
PLoS Pathog. 2018 Apr 9;14(4):e1006981. doi: 10.1371/journal.ppat.1006981. eCollection 2018 Apr.PMID: 29630665Free PMC article.
The absence of N-acetylglucosamine in wall teichoic acids of Listeria monocytogenes modifies biofilm architecture and tolerance to rinsing and cleaning procedures.
Brauge T, Faille C, Sadovskaya I, Charbit A, Benezech T, Shen Y, Loessner MJ, Bautista JR, Midelet-Bourdin G.
PLoS One. 2018 Jan 10;13(1):e0190879. doi: 10.1371/journal.pone.0190879. eCollection 2018.PMID: 29320565Free PMC article.
2017
Type I interferon-mediated autoinflammation due to DNase II deficiency.
Rodero MP, Tesser A, Bartok E, Rice GI, Della Mina E, Depp M, Beitz B, Bondet V, Cagnard N, Duffy D, Dussiot M, Frémond ML, Gattorno M, Guillem F, Kitabayashi N, Porcheray F, Rieux-Laucat F, Seabra L, Uggenti C, Volpi S, Zeef LAH, Alyanakian MA, Beltrand J, Bianco AM, Boddaert N, Brouzes C, Candon S, Caorsi R, Charbit M, Fabre M, Faletra F, Girard M, Harroche A, Hartmann E, Lasne D, Marcuzzi A, Neven B, Nitschke P, Pascreau T, Pastore S, Picard C, Picco P, Piscianz E, Polak M, Quartier P, Rabant M, Stocco G, Taddio A, Uettwiller F, Valencic E, Vozzi D, Hartmann G, Barchet W, Hermine O, Bader-Meunier B, Tommasini A, Crow YJ.
Nat Commun. 2017 Dec 19;8(1):2176. doi: 10.1038/s41467-017-01932-3.PMID: 29259162Free PMC article.
Antibacterial Toxins: Gram-Positive Bacteria Strike Back!
Jamet A, Charbit A, Nassif X.
Trends Microbiol. 2018 Feb;26(2):89-91. doi: 10.1016/j.tim.2017.11.003. Epub 2017 Nov 21.PMID: 29174101
Peripheral blood vessels are a niche for blood-borne meningococci.
Capel E, Barnier JP, Zomer AL, Bole-Feysot C, Nussbaumer T, Jamet A, Lécuyer H, Euphrasie D, Virion Z, Frapy E, Pélissier P, Join-Lambert O, Rattei T, Bourdoulous S, Nassif X, Coureuil M.
Virulence. 2017 Nov 17;8(8):1808-1819. doi: 10.1080/21505594.2017.1391446. Epub 2017 Nov 27.PMID: 29099305Free PMC article.
Covariate selection for association screening in multiphenotype genetic studies.
Aschard H, Guillemot V, Vilhjalmsson B, Patel CJ, Skurnik D, Ye CJ, Wolpin B, Kraft P, Zaitlen N.
Nat Genet. 2017 Dec;49(12):1789-1795. doi: 10.1038/ng.3975. Epub 2017 Oct 16.PMID: 29038595Free PMC article.
The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella.
Ziveri J, Tros F, Guerrera IC, Chhuon C, Audry M, Dupuis M, Barel M, Korniotis S, Fillatreau S, Gales L, Cahoreau E, Charbit A.
Nat Commun. 2017 Oct 11;8(1):853. doi: 10.1038/s41467-017-00889-7.PMID: 29021545Free PMC article.
Cryoelectron Microscopy Reconstructions of the Pseudomonas aeruginosa and Neisseria gonorrhoeae Type IV Pili at Sub-nanometer Resolution.
Wang F, Coureuil M, Osinski T, Orlova A, Altindal T, Gesbert G, Nassif X, Egelman EH, Craig L.
Structure. 2017 Sep 5;25(9):1423-1435.e4. doi: 10.1016/j.str.2017.07.016.PMID: 28877506
A widespread family of polymorphic toxins encoded by temperate phages.
Jamet A, Touchon M, Ribeiro-Gonçalves B, Carriço JA, Charbit A, Nassif X, Ramirez M, Rocha EPC.
BMC Biol. 2017 Aug 29;15(1):75. doi: 10.1186/s12915-017-0415-1.PMID: 28851366Free PMC article.
Intracellular Survival of Staphylococcus aureus in Endothelial Cells: A Matter of Growth or Persistence.
Rollin G, Tan X, Tros F, Dupuis M, Nassif X, Charbit A, Coureuil M.
Front Microbiol. 2017 Jul 19;8:1354. doi: 10.3389/fmicb.2017.01354. eCollection 2017.PMID: 28769913Free PMC article.
Intradermal Immunization with rAAV1 Vector Induces Robust Memory CD8+ T Cell Responses Independently of Transgene Expression in DCs.
Ghenassia A, Gross DA, Lorain S, Tros F, Urbain D, Benkhelifa-Ziyyat S, Charbit A, Davoust J, Chappert P.
Mol Ther. 2017 Oct 4;25(10):2309-2322. doi: 10.1016/j.ymthe.2017.06.019. Epub 2017 Jul 15.PMID: 28720467Free PMC article.
A virulence-associated filamentous bacteriophage of Neisseria meningitidis increases host-cell colonisation.
Bille E, Meyer J, Jamet A, Euphrasie D, Barnier JP, Brissac T, Larsen A, Pelissier P, Nassif X.
PLoS Pathog. 2017 Jul 13;13(7):e1006495. doi: 10.1371/journal.ppat.1006495. eCollection 2017 Jul.PMID: 28704569Free PMC article.
Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β2-adrenoceptor clusters assembled by alpha-actinin-4.
Maïssa N, Covarelli V, Janel S, Durel B, Simpson N, Bernard SC, Pardo-Lopez L, Bouzinba-Ségard H, Faure C, Scott MGH, Coureuil M, Morand PC, Lafont F, Nassif X, Marullo S, Bourdoulous S.
Nat Commun. 2017 Jun 1;8:15764. doi: 10.1038/ncomms15764.PMID: 28569760Free PMC article.
Importance of Metabolic Adaptations in Francisella Pathogenesis.
Ziveri J, Barel M, Charbit A.
Front Cell Infect Microbiol. 2017 Mar 28;7:96. doi: 10.3389/fcimb.2017.00096. eCollection 2017.PMID: 28401066Free PMC article.Review.
Role of Glycosylation/Deglycolysation Processes in Francisella tularensis Pathogenesis.
Barel M, Charbit A.
Front Cell Infect Microbiol. 2017 Mar 21;7:71. doi: 10.3389/fcimb.2017.00071. eCollection 2017.PMID: 28377902Free PMC article.Review.
Pathogenesis of meningococcal purpura fulminans.
Lécuyer H, Borgel D, Nassif X, Coureuil M.
Pathog Dis. 2017 Apr 1;75(3). doi: 10.1093/femspd/ftx027.PMID: 28334263Review.
A journey into the brain: insight into how bacterial pathogens cross blood-brain barriers.
Coureuil M, Lécuyer H, Bourdoulous S, Nassif X.
Nat Rev Microbiol. 2017 Mar;15(3):149-159. doi: 10.1038/nrmicro.2016.178. Epub 2017 Jan 16.PMID: 28090076Review.
2016
Structure of the Neisseria meningitidis Type IV pilus.
Kolappan S, Coureuil M, Yu X, Nassif X, Egelman EH, Craig L.
Nat Commun. 2016 Oct 4;7:13015. doi: 10.1038/ncomms13015.PMID: 27698424Free PMC article.
Comprehensive Identification of Meningococcal Genes and Small Noncoding RNAs Required for Host Cell Colonization.
Capel E, Zomer AL, Nussbaumer T, Bole C, Izac B, Frapy E, Meyer J, Bouzinba-Ségard H, Bille E, Jamet A, Cavau A, Letourneur F, Bourdoulous S, Rattei T, Nassif X, Coureuil M.
mBio. 2016 Aug 2;7(4):e01173-16. doi: 10.1128/mBio.01173-16.PMID: 27486197Free PMC article.
Experimental Evidence of Bacterial Colonization of Human Coronary Microvasculature and Myocardial Tissue during Meningococcemia.
Bergounioux J, Coureuil M, Belli E, Ly M, Cambillau M, Goudin N, Nassif X, Join-Lambert O.
Infect Immun. 2016 Sep 19;84(10):3017-23. doi: 10.1128/IAI.00420-16. Print 2016 Oct.PMID: 27481255Free PMC article.
Manipulation of host membranes by the bacterial pathogens Listeria, Francisella, Shigella and Yersinia.
Pizarro-Cerdá J, Charbit A, Enninga J, Lafont F, Cossart P.
Semin Cell Dev Biol. 2016 Dec;60:155-167. doi: 10.1016/j.semcdb.2016.07.019. Epub 2016 Jul 19.PMID: 27448494Free PMC article.Review.
Host glycosylation pathways and the unfolded protein response contribute to the infection by Francisella.
Barel M, Harduin-Lepers A, Portier L, Slomianny MC, Charbit A.
Cell Microbiol. 2016 Dec;18(12):1763-1781. doi: 10.1111/cmi.12614. Epub 2016 Jun 3.PMID: 27185209
Characterization of MDAΦ, a temperate filamentous bacteriophage of Neisseria meningitidis.
Meyer J, Brissac T, Frapy E, Omer H, Euphrasie D, Bonavita A, Nassif X, Bille E.
Microbiology. 2016 Feb;162(2):268-282. doi: 10.1099/mic.0.000215. Epub 2015 Nov 24.PMID: 26602366
2015
Efficacy of ertapenem in severe hidradenitis suppurativa: a pilot study in a cohort of 30 consecutive patients.
Join-Lambert O, Coignard-Biehler H, Jais JP, Delage M, Guet-Revillet H, Poirée S, Duchatelet S, Jullien V, Hovnanian A, Lortholary O, Nassif X, Nassif A.
J Antimicrob Chemother. 2016 Feb;71(2):513-20. doi: 10.1093/jac/dkv361. Epub 2015 Nov 12.PMID: 26565016
Remission of refractory pyoderma gangrenosum, severe acne, and hidradenitis suppurativa (PASH) syndrome using targeted antibiotic therapy in 4 patients.
Join-Lambert O, Duchatelet S, Delage M, Miskinyte S, Coignard H, Lemarchand N, Alemy-Carreau M, Lortholary O, Nassif X, Hovnanian A, Nassif A.
J Am Acad Dermatol. 2015 Nov;73(5 Suppl 1):S66-9. doi: 10.1016/j.jaad.2015.07.040.PMID: 26470620
Bacteriology of hidradenitis suppurativa/acne inversa: A review.
Nikolakis G, Join-Lambert O, Karagiannidis I, Guet-Revillet H, Zouboulis CC, Nassif A.
J Am Acad Dermatol. 2015 Nov;73(5 Suppl 1):S12-8. doi: 10.1016/j.jaad.2015.07.041.PMID: 26470608Review.
Gluconeogenesis, an essential metabolic pathway for pathogenic Francisella.
Brissac T, Ziveri J, Ramond E, Tros F, Kock S, Dupuis M, Brillet M, Barel M, Peyriga L, Cahoreau E, Charbit A.
Mol Microbiol. 2015 Oct;98(3):518-34. doi: 10.1111/mmi.13139. Epub 2015 Sep 10.PMID: 26192619
Characterization of the Maf family of polymorphic toxins in pathogenic Neisseria species.
Jamet A, Nassif X.
Microb Cell. 2015 Mar 2;2(3):88-90. doi: 10.15698/mic2015.03.194.PMID: 28357281Free PMC article.
The complex amino acid diet of Francisella in infected macrophages.
Barel M, Ramond E, Gesbert G, Charbit A.
Front Cell Infect Microbiol. 2015 Feb 6;5:9. doi: 10.3389/fcimb.2015.00009. eCollection 2015.PMID: 25705612Free PMC article.Review.
Contribution of the multiple Type I signal peptidases to the secretome of Listeria monocytogenes: deciphering their specificity for secreted exoproteins by exoproteomic analysis.
Renier S, Chafsey I, Chambon C, Caccia N, Charbit A, Hébraud M, Desvaux M.
J Proteomics. 2015 Mar 18;117:95-105. doi: 10.1016/j.jprot.2015.01.007. Epub 2015 Jan 28.PMID: 25637307
Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts.
Ramond E, Gesbert G, Guerrera IC, Chhuon C, Dupuis M, Rigard M, Henry T, Barel M, Charbit A.
Mol Cell Proteomics. 2015 Apr;14(4):870-81. doi: 10.1074/mcp.M114.044552. Epub 2015 Jan 23.PMID: 25616868Free PMC article.
A new family of secreted toxins in pathogenic Neisseria species.
Jamet A, Jousset AB, Euphrasie D, Mukorako P, Boucharlat A, Ducousso A, Charbit A, Nassif X.
PLoS Pathog. 2015 Jan 8;11(1):e1004592. doi: 10.1371/journal.ppat.1004592. eCollection 2015 Jan.PMID: 25569427Free PMC article.
Importance of branched-chain amino acid utilization in Francisella intracellular adaptation.
Gesbert G, Ramond E, Tros F, Dairou J, Frapy E, Barel M, Charbit A.
Infect Immun. 2015 Jan;83(1):173-83. doi: 10.1128/IAI.02579-14. Epub 2014 Oct 20.PMID: 25332124Free PMC article.
2014
Invasive meningococcal disease: a disease of the endothelial cells.
Coureuil M, Bourdoulous S, Marullo S, Nassif X.
Trends Mol Med. 2014 Oct;20(10):571-8. doi: 10.1016/j.molmed.2014.08.002. Epub 2014 Aug 29.PMID: 25178566Review.
Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization.
Bernard SC, Simpson N, Join-Lambert O, Federici C, Laran-Chich MP, Maïssa N, Bouzinba-Ségard H, Morand PC, Chretien F, Taouji S, Chevet E, Janel S, Lafont F, Coureuil M, Segura A, Niedergang F, Marullo S, Couraud PO, Nassif X, Bourdoulous S.
Nat Med. 2014 Jul;20(7):725-31. doi: 10.1038/nm.3563. Epub 2014 Jun 1.PMID: 24880614Free PMC article.