Auteurs
Zaidan M, Burtin M, Zhang JD, Blanc T, Barre P, Garbay S, Nguyen C, Vasseur F, Yammine L, Germano S, Badi L, Gubler MC, Gallazzini M, Friedlander G, Pontoglio M, Terzi F
Signaling pathways predisposing to chronic kidney disease progression
Date revue
Doi
10.1172/jci.insight.126183
Revue
JCI Insight
Auteurs
Cohen C, Le Goff O, Soysouvanh F, Vasseur F, Tanou M, Nguyen C, Amrouche L, Le Guen J, Saltel-Fulero O, Meunier T, Nguyen-Khoa T, Rabant M, Nochy D, Legendre C, Friedlander G, Childs BG, Baker DJ, Knebelmann B, Anglicheau D, Milliat F, Terzi F
Glomerular endothelial cell senescence drives age-related kidney disease through PAI-1
Date revue
Doi
10.15252/emmm.202114146
Revue
EMBO Mol Med
Auteurs
Laouari D, Vergnaud P, Hirose T, Zaidan M, Rabant M, Nguyen C, Burtin M, Legendre C, Codogno P, Friedlander G, Anglicheau D, Terzi F
The sexual dimorphism of kidney growth in mice and humans
Date revue
Doi
10.1016/j.kint.2022.02.027
Revue
Kidney Int
Auteurs
Isnard P, Vergnaud P, Garbay S, Jamme M, Eloudzeri M, Karras A, Anglicheau D, Galantine V, Jalal Eddine A, Gosset C, Pourcine F, Zarhrate M, Gibier JB, Rensen E, Pietropaoli S, Barba-Spaeth G, Duong-Van-Huyen JP, Molina TJ, Mueller F, Zimmer C, Pontoglio M, Terzi F, Rabant M
A specific molecular signature in SARS-CoV-2-infected kidney biopsies
Date revue
Doi
10.1172/jci.insight.165192
Revue
JCI Insight
Auteurs
Patitucci C, Couchy G, Bagattin A, Cañeque T, de Reyniès A, Scoazec JY, Rodriguez R, Pontoglio M, Zucman-Rossi J, Pende M, Panasyuk G
Hepatocyte nuclear factor 1α suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription
Date revue
Doi
10.1172/JCI90327
Revue
J Clin Invest
Auteurs
Niemir N, Rouvière L, Besse A, Vanier MT, Dmytrus J, Marais T, Astord S, Puech JP, Panasyuk G, Cooper JD, Barkats M, Caillaud C
Intravenous administration of scAAV9-Hexb normalizes lifespan and prevents pathology in Sandhoff disease mice
Date revue
Doi
10.1093/hmg/ddy012
Revue
Hum Mol Genet
Auteurs
Iershov A, Nemazanyy I, Alkhoury C, Girard M, Barth E, Cagnard N, Montagner A, Chretien D, Rugarli EI, Guillou H, Pende M, Panasyuk G
The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα
Date revue
Doi
10.1038/s41467-019-09598-9
Revue
Nat Commun
Auteurs
Shibayama Y, Alkhoury C, Nemazanyy I, F Henneman N, Cagnard N, Girard M, Atsumi T, Panasyuk G
Class 3 phosphoinositide 3-kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity
Date revue
Doi
10.1111/apha.13793
Revue
Acta Physiol (Oxf)
Auteurs
Alkhoury C, Henneman NF, Petrenko V, Shibayama Y, Segaloni A, Gadault A, Nemazanyy I, Le Guillou E, Wolide AD, Antoniadou K, Tong X, Tamaru T, Ozawa T, Girard M, Hnia K, Lutter D, Dibner C, Panasyuk G
Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis
Date revue
Doi
10.1038/s41556-023-01171-3
Revue
Nat Cell Biol
Auteurs
Sokal A, Chappert P, Barba-Spaeth G, Roeser A, Fourati S, Azzaoui I, Vandenberghe A, Fernandez I, Meola A, Bouvier-Alias M, Crickx E, Beldi-Ferchiou A, Hue S, Languille L, Michel M, Baloul S, Noizat-Pirenne F, Luka M, Mégret J, Ménager M, Pawlotsky JM, Fillatreau S, Rey FA, Weill JC, Reynaud CA, Mahévas M
Maturation and persistence of the anti-SARS-CoV-2 memory B cell response
Date revue
Doi
10.1016/j.cell.2021.01.050
Revue
Cell