Last 30 publications
2020
Victor JR, Lezmi G, Leite-de-Moraes M.
New Insights into Asthma Inflammation: Focus on iNKT, MAIT, and gammadeltaT Cells.
Clin Rev Allergy Immunol. 2020 Apr 3; doi:10.1007/s12016-020-08784-8
Martin E, Minet N, Boschat AC, Sanquer S, Sobrino S, Lenoir C, de Villartay JP, Leite-de-Moraes M, Picard C, Soudais C, Bourne T, Hambleton S, Hughes SM, Wynn RF, Briggs TA, Genomics England Research C, Patel S, Lawrence MG, Fischer A, Arkwright PD, Latour S.
Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation.
JCI Insight. 2020 Mar 12; 5(5):doi:10.1172/jci.insight.133880
2019
Allali S, Dietrich C, Machavoine F, Rignault-Bricard R, Brousse V, de Montalembert M, Hermine O, Maciel TT, Leite-de-Moraes M. Innate-like T cells in children with sickle cell disease. PLoS One. 2019 14(6):e0219047. doi:10.1371/journal.pone.0219047
Belkadi A, Dietrich C, Machavoine F, Victor JR, Leite-de-Moraes M. gammadelta T cells amplify Blomia tropicalis-induced allergic airway disease. Allergy. 2019 Feb; 74(2):395-398. doi:10.1111/all.13618
Briand C, Fremond ML, Bessis D, Carbasse A, Rice GI, Bondet V, Duffy D, Chatenoud L, Blanche S, Crow YJ, Neven B. Efficacy of JAK1/2 inhibition in the treatment of chilblain lupus due to TREX1 deficiency. Ann Rheum Dis. 2019 Mar; 78(3):431-433. doi:10.1136/annrheumdis-2018-214037
Chatenoud L, Bertuccio P, Turati F, Galeone C, Naldi L, Chatenoud L, La Vecchia C, Bach JF, Group HS. Markers of microbial exposure lower the incidence of atopic dermatitis. Allergy. 2019 Jul 18; doi:10.1111/all.13990
Chatenoud L. A future for CD3 antibodies in immunotherapy of type 1 diabetes. Diabetologia. 2019 Apr; 62(4):578-581. doi:10.1007/s00125-018-4808-7
Courbette O, Aupiais C, Viala J, Hugot JP, Louveau B, Chatenoud L, Bourrat E, Martinez-Vinson C. Infliximab Paradoxical Psoriasis in a Cohort of Children With Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2019 Aug; 69(2):189-193. doi:10.1097/MPG.0000000000002349
de-Oliveira MG, Lira AAL, Sgnotto FR, Inoue AHS, Santos LS, Nakamatsu BY, Duarte AJS, Leite-de-Moraes M, Victor JR. Maternal IgG impairs the maturation of offspring intrathymic IL-17-producing gammadeltaT cells: Implications for murine and human allergies. Clin Exp Allergy. 2019 Jul; 49(7):1000-1012. doi:10.1111/cea.13393
Duchatelet S, Join-Lambert O, Delage M, Miskinyte S, Guet-Revillet H, Lam T, Coignard-Biehler H, Ungeheuer MN, Chatenoud L, Lortholary O, Nassif X, Hovnanian A, Nassif AS. Remission of chronic acne fulminans and severe hidradenitis suppurativa with targeted antibiotherapy. JAAD Case Rep. 2019 Jun; 5(6):525-528. doi:10.1016/j.jdcr.2019.04.001
Lezmi G, Abou-Taam R, Garcelon N, Dietrich C, Machavoine F, Delacourt C, Adel-Patient K, Leite-de-Moraes M. Evidence for a MAIT-17-high phenotype in children with severe asthma. J Allergy Clin Immunol. 2019 Aug 16; doi:10.1016/j.jaci.2019.08.003c
Lozza L, Moura-Alves P, Domaszewska T, Lage Crespo C, Streata I, Kreuchwig A, Puyskens A, Bechtle M, Klemm M, Zedler U, Silviu Ungureanu B, Guhlich-Bornhof U, Koehler AB, Staber M, Mollenkopf HJ, Hurwitz R, Furkert J, Krause G, Weiner J, 3rd, Jacinto A, Mihai I, Leite-de-Moraes M, Siebenhaar F, Maurer M, Kaufmann SHE. The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis. Sci Rep. 2019 Jul 26; 9(1):10878. doi:10.1038/s41598-019-47350-x
Neven B, Diana JS, Castelle M, Magnani A, Rosain J, Touzot F, Moreira B, Fremond ML, Briand C, Bendavid M, Levy R, Morelle G, Vincent M, Magrin E, Bourget P, Chatenoud L, Picard C, Fischer A, Moshous D, Blanche S. Haploidentical Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide for Primary Immunodeficiencies and Inherited Disorders in Children. Biol Blood Marrow Transplant. 2019 Jul; 25(7):1363-1373. doi:10.1016/j.bbmt.2019.03.009
2018
Bach JF. The hygiene hypothesis in autoimmunity: the role of pathogens and commensals. Nat Rev Immunol. 2018;18(2):105-20. doi: 10.1038/nri.2017.111. PubMed PMID: 29034905.
Besancon A, Demir Z, Goncalves T, Valette F, Panafieu E, Chatenoud L, You S. Differential Impact of T-bet and IFNgamma on Pancreatic Islet Allograft Rejection. Transplantation. 2018 Sep; 102(9):1496-1504. doi:10.1097/TP.0000000000002261
Besancon A, Goncalves T, Valette F, Mary C, Vanhove B, Chatenoud L, You S. A selective CD28 antagonist and rapamycin synergise to protect against spontaneous autoimmune diabetes in NOD mice. Diabetologia. 2018;61(8):1811-6. doi: 10.1007/s00125-018-4638-7. PubMed PMID: 29845333
Besancon A, Goncalves T, Valette F, Dahllof MS, Mandrup-Poulsen T, Chatenoud L, You S. Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice. Diabetologia. 2018;61(2):389-98. doi: 10.1007/s00125-017-4459-0. PubMed PMID: 29030662
Briand C, Fremond ML, Bessis D, Carbasse A, Rice GI, Bondet V, Duffy D, Chatenoud L, Blanche S, Crow YJ, Neven B. Efficacy of JAK1/2 inhibition in the treatment of chilblain lupus due to TREX1 deficiency. Ann Rheum Dis. 2018. doi: 10.1136/annrheumdis-2018-214037. PubMed PMID: 30282666
Delliere S, Guery R, Candon S, Rammaert B, Aguilar C, Lanternier F, Chatenoud L, Lortholary O. Understanding Pathogenesis and Care Challenges of Immune Reconstitution Inflammatory Syndrome in Fungal Infections. J Fungi (Basel). 2018 Dec 17; 4(4):doi:10.3390/jof4040139
Ghiasi SM, Dahllof MS, Osmai Y, Osmai M, Jakobsen KK, Aivazidis A, Tyrberg B, Perruzza L, Prause MCB, Christensen DP, Fog-Tonnesen M, Lundh M, Grassi F, Chatenoud L, Mandrup-Poulsen T. Regulation of the beta-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis. Mol Cell Endocrinol. 2018. doi: 10.1016/j.mce.2018.08.001. PubMed PMID: 30121202
Landon-Cardinal O, Friedman D, Guiguet M, Laforet P, Heming N, Salort-Campana E, Jouen F, Allenbach Y, Boyer O, Chatenoud L, Eymard B, Sharshar T, Benveniste O. Efficacy of Rituximab in Refractory Generalized anti-AChR Myasthenia Gravis. J Neuromuscul Dis. 2018;5(2):241-9. doi: 10.3233/JND-180300. PubMed PMID: 29865089
Lezmi G, Leite-de-Moraes M. Invariant Natural Killer T and Mucosal-Associated Invariant T Cells in Asthmatic Patients. Front Immunol. 2018;9:1766. doi: 10.3389/fimmu.2018.01766. PubMed PMID: 30105031; PubMed Central PMCID: PMCPMC6077286
Lezmi G, Abou Taam R, Dietrich C, Chatenoud L, de Blic J, Leite-de-Moraes M. Circulating IL-17-producing mucosal-associated invariant T cells (MAIT) are associated with symptoms in children with asthma. Clin Immunol. 2018;188:7-11. doi: 10.1016/j.clim.2017.11.009. PubMed PMID: 29196148.
Orabona C, Mondanelli G, Pallotta MT, Carvalho A, Albini E, Fallarino F, Vacca C, Volpi C, Belladonna ML, Berioli MG, Ceccarini G, Esposito SM, Scattoni R, Verrotti A, Ferretti A, De Giorgi G, Toni S, Cappa M, Matteoli MC, Bianchi R, Matino D, Iacono A, Puccetti M, Cunha C, Bicciato S, Antognelli C, Talesa VN, Chatenoud L, Fuchs D, Pilotte L, Van den Eynde B, Lemos MC, Romani L, Puccetti P, Grohmann U. Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1in juvenile diabetes. JCI Insight. 2018;3(6). doi: 10.1172/jci.insight.96244. PubMed PMID: 29563329; PubMed Central PMCID: PMCPMC5926942
Rignault-Bricard R, Machavoine F, Mecheri S, Hermine O, Schneider E, Dy M*, Leite-de-Moraes M*. IL-3-producing basophils are required to exacerbate airway hyper-responsiveness in a murine inflammatory model. Allergy. 2018. doi: 10.1111/all.13480. PubMed PMID: 29777594
* corresponding authors
You S, Chatenoud L. Revisiting the phenotypic and genetic profiling of anergic T cells mediating long-term transplant tolerance. Curr Opin Organ Transplant. 2018;23(1):83-9. doi: 10.1097/MOT.0000000000000494. PubMed PMID: 29194071