Welcome on the Necker-Enfants Malades Institute website
Wednesday 31 of January, 2024
New Marker for Cardiovascular Risk in Type 2 Diabetes Patients – Our researchers in the spotlight

A novel prognostic marker for cardiovascular risk in individuals with type 2 diabetes (T2D) has been identified by the IMMEDIAB team – Immunity and Metabolism in Diabetes, led by Nicolas Venteclef at INEM.

This breakthrough, the result of collective and collaborative efforts, positions our researchers at the forefront of a significant scientific leap.

The study, involving phenotypic, transcriptomic, and metabolomic analyses across three cohorts of T2D patients - Angiosafe, GLUTADIAB, and SURDIAGENE - reveals a correlation between the number of circulating monocytes and an increased risk of cardiovascular events such as stroke or myocardial infarction over a decade.

Published in Circulation Research and highlighted in an INSERM press release, this work is a substantial step forward in understanding, assessing, and preventing cardiovascular incidents in type 2 diabetic patients.

With a patent already filed for this discovery and the ongoing development of a cutting-edge electronic sensor for measuring circulating monocytes from a single drop of blood, this innovation promises to transform patient care.

The potential impact of this research on the cardiovascular health of millions of people with type 2 diabetes is immense, ushering in new and promising horizons in the medical field.

To read the press release: inserm press

To learn more about the study: Circulation Research

Address

Notice: Undefined variable: contact_addr in /homepages/40/d483507699/htdocs/location.php on line 21
Support(s)
HRH Princess Caroline of Hanover, who through the Princess Grace Foundation, already supports medical research and anything that helps to relieve the sick children in France and around the world, has agreed to commit to our side so that our Center of Molecular medicine continues to meet the current challenges and fight diseases, and in particular the ones affecting children.

INEM - Organigramme