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Jeudi 24 août 2023
Just published in Cell Reports: Lipocalin-2 induces mitochondrial dysfunction in renal tubular cells via mTOR pathway activation

Mitochondrial dysfunction is a critical process involved in plethora of pathologies. Morgan Gallazzini’s group in the team of Fabiola Terzi identified Lipocalin-2 as an inducer of mitochondrial dysfunction. By combining in cells and in vivo renal disease models the team demonstrated that Lipocalin-2 regulates mTOR activity and thus induces mitochondrial fragmentation and loss of function.

This work has been published in Cell Reports and is available to read at the following link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01043-4

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Parrain(s)
S.A.R. la Princesse Caroline de Hanovre qui, à travers la Fondation Princesse Grace, soutient déjà la recherche medicale et tout ce qui contribue à soulager les enfants malades en France et dans le monde, a accepté de s'engager à nos cotés pour que ce centre de medecine moleculaire, tourné entre autres vers les pathologies des enfants, prenne de vitesse les maladies et continue à relever les defis actuels.

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