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Thursday 24 of August, 2023
Just published in Cell Reports: Lipocalin-2 induces mitochondrial dysfunction in renal tubular cells via mTOR pathway activation

Mitochondrial dysfunction is a critical process involved in plethora of pathologies. Morgan Gallazzini’s group in the team of Fabiola Terzi identified Lipocalin-2 as an inducer of mitochondrial dysfunction. By combining in cells and in vivo renal disease models the team demonstrated that Lipocalin-2 regulates mTOR activity and thus induces mitochondrial fragmentation and loss of function.

This work has been published in Cell Reports and is available to read at the following link:


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HRH Princess Caroline of Hanover, who through the Princess Grace Foundation, already supports medical research and anything that helps to relieve the sick children in France and around the world, has agreed to commit to our side so that our Center of Molecular medicine continues to meet the current challenges and fight diseases, and in particular the ones affecting children.

INEM - Organigramme