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Friday 14 of July, 2023
Just published in Nature Cell Biology
Just published in NCB: the team of Ganna Panasyuk made a surprising discovery that Class 3 phosphatidylinositol-3-kinase (PI3K), the best known for its role as a lipid kinase in vesicular trafficking and lysosomal degradation by autophagy, has a function in nuclear transcription. By combining the analyses in cells and in vivo in liver the team demonstrated that class 3 PI3K acts as a coactivator of the circadian clock Bmal1–Clock transcription factor complex for rhythmic purine nucleotides metabolism. This finding opens new doors for the roles of nuclear subunits of class 3 PI3K in metabolic homeostasis. 
See more in: https://rdcu.be/dgd8k and https://rdcu.be/dgiUF

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HRH Princess Caroline of Hanover, who through the Princess Grace Foundation, already supports medical research and anything that helps to relieve the sick children in France and around the world, has agreed to commit to our side so that our Center of Molecular medicine continues to meet the current challenges and fight diseases, and in particular the ones affecting children.

INEM - Organigramme