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Bienvenu(e) sur le site de l'Institut Necker Enfants Malades
Vendredi 30 octobre 2020
Cell Reports _ Developmental Renal Glomerular Defects at the Origin of Glomerulocystic Disease

The research group led by Marco Pontoglio at the “Institut Necker Enfants Malades” has discovered a novel genetically programmed morphogenetic process that plays an important role in renal glomerulogenesis. The dysfunction of this process leads to self-strangled glomeruli that generate cysts upon glomerular filtration. This process tackles a so far unappreciated developmental issue: the separation of the urinary and vascular poles in early nephron precursors. This study is published in Cell Reports 2020 Oct 27;33(4):108304. DOI:https://doi.org/10.1016/j.celrep.2020.108304

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Parrain(s)
S.A.R. la Princesse Caroline de Hanovre qui, à travers la Fondation Princesse Grace, soutient déjà la recherche medicale et tout ce qui contribue à soulager les enfants malades en France et dans le monde, a accepté de s'engager à nos cotés pour que ce centre de medecine moleculaire, tourné entre autres vers les pathologies des enfants, prenne de vitesse les maladies et continue à relever les defis actuels.

INEM - Organigramme