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Wednesday 31 of January, 2024
Découverte d’un nouveau marqueur de risque cardiovasculaire chez les patients DT2 - Nos chercheurs à l’honneur
Un nouveau marqueur pronostic de risque cardiovasculaire chez les personnes atteintes de diabète de type 2 (DT2) a été identifié par l’équipe IMMEDIAB – Immunité et Métabolisme dans le Diabète, dirigée par Nicolas Venteclef à l’INEM.
Cette avancée, résultat d'un effort collectif et collaboratif, [...]
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Wednesday 31 of January, 2024
New Marker for Cardiovascular Risk in Type 2 Diabetes Patients – Our researchers in the spotlight
A novel prognostic marker for cardiovascular risk in individuals with type 2 diabetes (T2D) has been identified by the IMMEDIAB team – Immunity and Metabolism in Diabetes, led by Nicolas Venteclef at INEM.
This breakthrough, the result of collective and collaborative efforts, positions our researchers at the [...]
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Monday 15 of January, 2024
Unlocking the Mysteries of Brain Function - New Publication in Cell Death & Disease by Integrative Neurobiology team

Slc20a1 and Slc20a2 regulate neuronal plasticity and cognition independently of their phosphate transport ability

In recent years, significant strides have been made in understanding rare neurological diseases like Primary Familial Brain Calcification (PFBC) an inherited form of neurological disorder with a wide spectrum of cognitive aspects. This condition has been associated with mutations in the sodium (Na)-Phosphate (Pi) co-transporter SLC20A2.
However, the etiology of brain [...]
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Monday 18 of December, 2023
Hommage au Professeur Jean-François Bach

C'est avec une profonde tristesse que nous vous faisons part du décès du Professeur Jean-François Bach, survenu le 12 décembre 2023 à l'âge de 83 ans. Le Professeur Bach a consacré l'intégralité de sa carrière en tant que médecin et scientifique à l'hôpital Necker, marquant de son empreinte plusieurs domaines de l'immunologie.

Initialement membre du service du Professeur Hamburger, le Professeur [...]

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Friday 8 of December, 2023
Just published: Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle
In their recently published study, Xiongqi Ding et al. (Team Pathogenesis of systemic infections) shed light on a critical aspect of chronic lung diseases : how the airway environment influences the behavior of S. aureus, a key player in these infections, particularly cystic fibrosis (CF).
Study Highlights
The study explores how S. aureus, a common opportunistic pathogen, adapts to the lungs of CF patients.
Key discoveries include convergent evolution in S. aureus, with [...]
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Tuesday 5 of December, 2023
Just Published: The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells by Aurore Claude-Taupin
In their recently published paper in Nature Communications, Aurore Claude-Taupin et al. explore the critical role of shear stress, a known regulator of renal function, and its dysregulation in various kidney diseases.
Building on prior research highlighting the significance of primary cilium-dependent autophagy in kidney epithelial cells' response to fluid flow, a new dimension has emerged.
Key Insights
  • Nuclear YAP/TAZ's involvement in negatively regulating [...]
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Tuesday 28 of November, 2023
Just Published: Canonical and Non-Canonical Roles of SNX1 and SNX2 in Endosomal Membrane Dynamics by Juliane Da Graça
In their recent review, published in Contact CTC, Juliane Da Graça, from Morel Lab, deep-dives into the fascinating world of endosomal membrane dynamics, uncovering the multifaceted functions of Sorting Nexins (SNXs), particularly focusing on SNX1 and SNX2.
Navigating the Endosomal Landscape: SNX1 and SNX2 boast a membrane-curvature domain and a phosphoinositide-binding domain, anchoring them to the PI3P-positive surface of endosomes. This positioning facilitates interactions [...]
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Monday 6 of November, 2023
Pr Elizabeth Macintyre Receives the Prestigious Fondation Guillaumat-Piel 2023 Award from La Fondation pour la Recherche Médicale
We are delighted to announce that Elizabeth Macintyre one of our distinguished researchers and co-leader of the Normal and pathological lymphoid differentiation Team, has been honored with the Fondation Guillaumat-Piel 2023 Award from La Fondation pour la Recherche Médicale. This recognition underscores the exceptional contributions of our faculty members and the cutting-edge research conducted within our institution.
Professor Macintyre was recognized for her groundbreaking work in [...]
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HRH Princess Caroline of Hanover, who through the Princess Grace Foundation, already supports medical research and anything that helps to relieve the sick children in France and around the world, has agreed to commit to our side so that our Center of Molecular medicine continues to meet the current challenges and fight diseases, and in particular the ones affecting children.

INEM - Organigramme